Real Madrid vs. RB Leipzig prediction and odds: 2024 UEFA Champions League choices, best bets by verified expert.

On Tuesday, the Red Bull Arena in Leipzig, Germany, will host a UEFA Champions League encounter. Real Madrid travels to RB Leipzig in the opening leg of a two-game Round of 16 contest with an aggregate score. The encounter opens the knockout stage for both teams, with RB Leipzig winning the most previous meeting between the clubs on Matchday 5 last year. RB Leipzig is also hosting just their third encounter against a Spanish team.
Kickoff is set at 3 p.m. ET. Real Madrid is the +125 favorite (risk $100 to win $125) in the most recent RB Leipzig vs. Real Madrid odds. Leipzig is a +200 underdog, a draw is worth +270, and the total goals scored is 2.5. Before you make any Real Madrid vs. RB Leipzig choices or UEFA Champions League predictions, check out what verified soccer expert Jon Eimer has to say.

Eimer is a high-volume bettor with extensive knowledge of leagues and players throughout the world. Since joining SportsLine, he has covered the English Premier League, Serie A, the FA Cup, and several other events. In 2023, he was on fire, going 248-234-12 for a $2,593 profit on $100 wagers. This featured an 86-59-5 Premier League record for $3,463 profit.
Eimer has now analyzed RB Leipzig vs. Real Madrid from every perspective and has delivered his Champions League predictions. Visit SportsLine right now to see Eimer’s choices. Here are the betting odds and trends for Real Madrid vs. RB Leipzig.
• The money line for RB Leipzig vs. Real Madrid is Real Madrid +125, RB Leipzig +200, and Draw +270.
• RB Leipzig vs. Real Madrid spread: Real Madrid -0.5 (+130).
• RB Leipzig vs. Real Madrid over/under: 2.5 goals.
• Picks for the match between RB Leipzig and Real Madrid: See choices at SportsLine.
Why You Should Back RB Leipzig
RB Leipzig has advanced to the Champions League knockout phase in four of the previous five seasons, and the team has won two German Cups, including the 2023 championship. RB Leipzig has 11 victories and five ties in its previous 19 home games against European rivals, and the team’s offensive is strong. Leipzig scored 13 goals and 12 assists during the group stage, and the team has 46 goals in its past 21 domestic games.
Leipzig’s forward Lois Openda leads the team with 15 goals in 21 Bundesliga games. He has scored in four consecutive matches and has four goals in five Champions League games in 2023-24. Real Madrid, on the other hand, will be missing Jude Bellingham in this encounter after injuring his ankle against Girona on Saturday. Bellingham is Real Madrid’s leading scorer this season, with 20 goals throughout tournaments and 16 goals in La Liga matches.
Why You Should Back Real Madrid
While Bellingham is out, Vinicius Junior will lead Real Madrid’s powerful attacking assault. He scored a goal and provided two assists in Real Madrid’s recent 4-0 victory against Girona, and he now has 12 goals and seven assists in all competitions this season. Real Madrid has 16 Champions League goals this season, the third most in the league, while the team is in the top four in possession (58.5%) and passing accuracy (92.8%). Real Madrid has 12 assists and just seven goals allowed in UCL play.
Real Madrid has a 28-year record of reaching the UEFA Champions League knockout phase. This includes 20 group victories, and Real Madrid won the UCL in 2021-22. This year, Real Madrid is one of just two unbeaten teams in the group stage, winning all six games and finishing eight points ahead of Napoli. Real Madrid has won ten of the past twelve games in all competitions, while Leipzig has only won once in the last four.
How to choose RB Leipzig vs. Real Madrid
Eimer has analyzed Tuesday’s game from every perspective and believes the goal total will be higher. He has also locked in three confident best bets, including one that pays out, and is providing a comprehensive preview of this Champions League match. He only shares his UEFA Champions League choices and insights on SportsLine.

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